Oxymetazoline Hydrochloride is a topical nasal decongestant that is often found in most OTC nasal sprays like Otrivin in India. It works quite effectively with regards to relieving people from nasal congestion caused by things like colds, allergies, or sinusitis by constricting blood vessels in the nasal passages. The medication is an alpha-adrenergic receptor binder, meaning that it binds to the alpha-adrenergic receptors. These receptors are found on the smooth muscle cells which line blood vessels in the nasal mucosa. When oxymetazoline is applied to the nasal mucosa through droplets, it stimulates the receptors and triggers them to cause constriction of nasal blood vessels. Through vasoconstriction, there is a reduce in blood flow to the region, causing decreased swelling and inflammation. It also reduces how much mucus is produced, since it reduces the quantity of fluid that leaks into the passages. Thus, air can flow more freely in the passage, providing relief from the blocked n...
Beta-blockers are commonly prescribed medications for people with cardiovascular problems like coronary artery disease. A lot of people take them, and a lot of them get great results with it. But there's something that most people don't know about them, beta-blockers interact with diabetic peoples' bodies in a way that can REALLY complicate treatment plans. For example, beta-blockers can mask the symptoms of hypoglycemia by reducing rapid heartbeats, tremors and anxiety. Although this seems good to someone with diabetes, it's actually worse. Without the typical warning signs of low blood sugar, patients may not be able to find a sugar source in time before they faint or get injured. Some non-selective beta-blockers also worsen diabetes, since they reduce insulin sensitivity, which obviously makes it way harder to manage blood glucose levels. Non-selective beta blockers also interfere with the metabolism of glucose, and worsen control over blood sugar. That's why s...