In a world where fungal infections are becoming more and more common with varying types of environments for fungal growth, itraconazole tends to come in handy for doctors and patients as a valuable tool to get rid of most stubborn, every-day fungi. This article discusses how it works, where itraconazole can be applied, how it’s applied, potential side-effects, and who should use this medicine.
Itraconazole
is an azole antifungal medication which works by inhibiting growth and fungi
replication. It works by ensuring that ergosterol is not produced in fungal
cell membranes (a core component of those membranes). Without ergosterol, these
cell membranes get weakened and are more susceptible to damage, leading to
eventual cell death.
This
medication is often used to treat diseases like onychomycosis (fungal
nail infections), skin infections (ringworm, jock itch, and athlete’s
foot), oral thrush (caused by candida), aspergillosis, histoplasmosis,
and even some lung infections.
Although
this medicine is highly useful and is often prescribed to patients with fungal
infections, it can sometimes be unsafe for pregnant/nursing women unless
prescribed by a certified healthcare provider, and can cause problems for those
with existing liver issues (itraconazole can hinder liver
function), and those on other medicines that may clash with how itraconazole
works.
All in
all, itraconazole works through disrupting cell membranes of fungal cells and
is a powerful tool in the fight against fungi. It is used to treat multiple infections,
with varying dosages depending on one’s condition and case. It is usually
consumed as a tablet, most often eaten after a meal or after drinking an acidic
drink. While side effects are possible with this medicine, itraconazole is generally
safe for a common audience and plays a crucial role for overall health.
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